Comfort and Convenience
Cabin temperature is a good example. Some people want airflow directed at them constantly, others find that unpleasant and prefer warmth at their feet, and the same setting rarely suits both front occupants at once.
Safety and Driver Assistance
It is worth learning where the essentials are while parked: hazard lights, demisting, mirror and wiper controls. Sorting that out before setting off means fewer distractions later, when conditions leave little time for searching.
Multimedia and Connectivity
Charging is the plainest need: a phone used for navigation drains quickly, so where a cable can sit without crossing the controls matters. Whether calls or music are handled through the car is a separate question.